허가사항 범위 내에서 아래와 같은 기준으로 투여 시 요양급여를 인정하며, 동 인정기준 이외에는 약값 전액을 환자가 부담토록 함.
- 아 래 -
○ 자궁내막증
가. 복강경검사 등으로 확진된 경우
나. 초음파검사 또는 자기공명영상으로 진단된 환자로서 난소, 직장, 방광에 생긴 경우
■ 고시 개정 고시번호(시행일자)
고시 제2018-253호(2018.12.1.)
■ 고시 개정 사유
교과서, 가이드라인, 임상연구문헌 등에서 언급한 난소, 직장, 방광에 생긴 자궁내막증 진단에 영상검사(초음파 및 자기공명검사)가 유용한 점 등을 고려하여 급여를 확대 함.
■ 관련문헌 등
· 박형무 외, 부인과학 제5판, (2015), 대한산부인과학회
· 조시현 외, 대한자궁내막증학회 임상진료지침, 2017, 제6차 학술대회 및 연수강좌
· Lobo Roger A, et al. Comprehensive Gynecology, 7th ed, 2017
· Conn's Current Therapy, 2018
· NICE Guideline (Published date: September 2017)
· ESHRE(European Society of Human Reproduction & Embryology) Guideline: Management of women with endometriosis, 2014,
· European Association of Urology. Guidelines on chronic pelvic pain. 2014
· World Endometriosis Society consensus, 2013
· ACOG Updates Guideline on Diagnosis and Treatment of Endometriosis, 2011
· Kim M et al. Guidelines For Management of Endometriosis, Korean journal of obsterics & gynecology, 2011
· Endometriosis: Diagnosis and Management, SOGC Clinical Practice Guideline, July 2010
· Consensus Guidelines for the Management of Chronic Pelvic Pain, SOGC Clinical Practice Guideline, No 164, Part one of two, August 2005
· The Management of Uterine Leiomyomas, SOGC Clinical Practice Guideline No. 318, February 2015
· NHS England
· Therapeutic management of uterine fibroid tumors: updated French guidelines, 2012
· Nisenblat V, Bossuyt PM et al. Imaging modalities for the non-invasive diagnosis of endometriosis. Cochrane Database Syst Rev. 2016 Feb 26;2:CD009591.
· Alborzi S, Rasekhi A et al. Diagnostic accuracy of magnetic resonance imaging, transvaginal, and transrectal ultrasonography in deep infiltrating endometriosis. Medicine (Baltimore). 2018 Feb;97(8):e9536.
· Ebert AD, Dong L et al. Dienogest 2 mg Daily in the Treatment of Adolescents with Clinically Suspected Endometriosis: The VISanne Study to Assess Safety in ADOlescents. J Pediatr Adolesc Gynecol. 2017 Oct;30(5):560-567.
· Lethaby A, Puscasiu L et al. Preoperative medical therapy before surgery for uterine fibroids. Cochrane Database Syst Rev. 2017 Nov 15;11:CD000547.
· Sohn GS, Cho S et al. Current medical treatment of uterine fibroids. Obstet Gynecol Sci. 2018 Mar;61(2):192-201.
· Lethaby A, Vollenhoven B et al. Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids. Cochrane Database Syst Rev. 2001;(2):CD000547.